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New Science Spotlight Articles
Every month, Fred Hutch postdoc writer/editors summarize two papers from each of our scientific divisions to stimulate collaborations across campus
June 03, 2025

A tale of two T-cells: comparing liso-cel and axi-cel for treatment of refractory large B-cell lymphoma
From the Gauthier group, Clinical Research Division

Cytomegalovirus has an activity shift following CAR T-cell therapy
From the Hill Group, Vaccine and Infectious Disease and Clinical Research Divisions

Gene therapy delivery system successfully targets CD90+ hematopoietic stem cells in vivo
Fred Hutch laboratory research presented at the American Society of Gene and Cell Therapy’s annual meeting moves a promising approach one step closer to clinical trials

Multiple myeloma is treatable, not curable. Is that set to change?
Some experts believe a ‘functional cure’ is already within reach

Now you see them, now you don’t: Gene editing protects stem cells from CAR T therapy
From the Kiem lab, Translational Science and Therapeutics Division

Fred Hutch research shines at national oncology conference
Society for Immunotherapy of Cancer meeting features new discoveries on cancer-cell visualization, T-cell survival and new targets for solid tumors

New initiative bolsters Washington state life sciences
Fred Hutch researchers awarded over $4M in grants from the Washington Research Foundation

Location, location, location: where is key for CAR T-cell therapy
From the Walter lab, Translational Science and Therapeutics Division

Histone mark profiling identifies KLF7 as critical for CAR-T cell proliferation
From the Henikoff lab, Translational Science and Therapeutics and Basic Sciences Divisions

A new era of COVID-19 brings new outlooks for cellular therapy recipients
From the Liu Group, Vaccine and Infectious Disease Division

TIME and space predict response to CAR T-cell therapy in lymphoma
From the Hirayama and Turtle labs, Clinical Research Division

Let’s give these CAR(T cell)s some pedals!
From Dr. Jacob Appelbaum, Fred Hutch Clinical Research Division and Seattle Children’s Therapeutics, Seattle Children’s Hospital

Detecting, detecting! A qPCR assay to detect WPRE sequences in CAR-T and TCR-T cells
From the Yeung lab, Translational Science and Therapeutics and Clinical Research Division

Automated, fast and accurate method to grade ICAHT, a CAR T-cell therapy side effect
From Dr. Emily Liang, Dr. Jordan Gauthier and colleagues, Clinical Research Division

Safety and feasibility approved for new therapy to treat relapsed hematologic malignancies
From the Bleakley Lab, Translational Science & Therapeutics Division

Fred Hutch and UW hematology-oncology fellows win ASCO Young Investigator Awards
Winners represent broad range of research

CAR T cell therapy targets HIV reservoirs to mitigate persistent HIV infection
From the Corey Lab, Vaccine and Infectious Disease Division

COVID-19 prior to cellular therapy is likely not a cause for alarm.
From the Hill Group, Clinical Research Division and Vaccine and Infectious Disease Division

Targeting B cells – a new approach to HIV treatment?
From the Peterson lab, Translational Science and Therapeutics Division